What This Is

The Immortality Index is an open-source, version-controlled binary milestone registry that decomposes the biological aging problem into 24 falsifiable research obstacles across two engineering tracks plus a shared System-Level Integration Bottleneck (SLIB) — the final convergence gate requiring both tracks to be simultaneously operational. Progress on each obstacle is determined solely by evidence from peer-reviewed literature — not prediction, personal estimate, or institutional position. The framework is designed for formal academic citation.

AI Authorship Disclosure

Theoretical Constructs

Several concepts in this framework — including System-Level Integration Bottlenecks (SLIB), Decentralized Intercellular Transcriptomic Error-Correction Networks, Somatic Identity Triage and Localized Fibrotic Encapsulation, and the G-5.2 2-of-3 spatial quorum logic gate — are original engineering constructs developed for this roadmap. They are not established clinical terminology. They represent formal engineering targets derived from extrapolating current biological and nanotechnology research trajectories and are intended as falsifiable specifications, not claims about currently operational systems.

AI Literature Scanning Methodology

Every six hours, an automated edge-worker pipeline uses large-language-model (LLM) analysis of peer-reviewed scientific literature to assess whether each milestone has been achieved. A milestone is confirmed only when: (1) the LLM returns high confidence with a specific journal citation; (2) all quantitative thresholds stated in the milestone are explicitly addressed; (3) sample size and experimental conditions match milestone requirements; and (4) evidence is from peer-reviewed primary literature, not conference abstracts or preprints without peer review. The double-confirmation requirement — threshold matching plus citation validation — is the primary false-positive elimination mechanism.

Benchmark Integrity

All milestone thresholds are pre-registered and immutable except via publicly visible pull requests with documented peer-reviewed justification. No threshold may be adjusted retroactively to accommodate an experimental result. The full change history of every threshold and milestone is permanently auditable in the public GitHub repository. The project is maintained anonymously to ensure assessments remain free from institutional affiliation, funding relationships, and individual reputational incentive.

Cite This Work

@misc{immortalityindex2026,
  author = {{Immortality Index}},
  title = {Immortality Index: A Binary Milestone Registry for Longevity Research},
  year = {2026},
  doi = {10.5281/zenodo.PLACEHOLDER},
  url = {https://github.com/immortalityindex/immortality-index}
}

APA: Immortality Index. (2026). Immortality Index: A Binary Milestone Registry for Longevity Research (v1.0.0). GitHub. https://doi.org/10.5281/zenodo.PLACEHOLDER

Not Medical Advice

Nothing on this site constitutes medical advice, investment advice, or a recommendation to pursue any specific intervention. All described technologies are research-stage unless otherwise noted.